Product Name :
SATB2 Mouse Monoclonal Antibody [4G03]
Predicted band size :
Observed band size :
Synonyms:
DNA binding protein SATB2 antibody DNA-binding protein SATB2 antibody FLJ21474 antibody FLJ32076 antibody GLSS antibody KIAA1034 antibody MGC119474 antibody MGC119477 antibody SATB family member 2 antibody SATB homeobox 2 antibody 展开
Function :
SATB2 (special AT-rich sequence-binding protein 2) is a nuclear matrix protein that influences craniofacial formation mechanisms, such as jaw and palate development, and is part of a transcriptional network regulating skeletal development and osteoblast differentiation. Highly expressed in adult and fetal brain, SATB2 contains two CUT DNA-binding domains and one homeobox domain and is closely related to SATB1, a transcriptional repressor. SATB2 is thought to bind to matrix attachment regions (MARs) and regulate MAR-dependent transcription of various genes, including HoxA2 and ATF-4 (CREB-2), involved in skeletal development. Functioning as both a transcriptional activator and repressor, SATB2 can also act as a protein scaffold that can enhance the activity of other DNA-binding proteins. Defects in the gene encoding SATB2 are the cause of cleft palate manifested in conjunction with severe mental retardation.
Antibody Type:
Mouse Monoclonal Antibody
Immunogen :
peptide
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IP, IF
Coupling :
unconjugated
Clone number:
4G03
RRID:
Form :
Liquid
Concentration :
2ug/ul
Storage instructions:
Store at +4℃
Storage buffer solution:
1.Taltobulin intermediate-1 Chemical name 0 ml of PBS with
Subtype:
IgG1
Purification method :
Protein A affinity purified.Price of 1-(2,2,2-Trifluoroethyl)piperazine
ELTSA :
Molecular weight :
105kDa
Positive control :
KNRK, HT-1080, SH-SY5Y