Product Name :
2-Isopropylmalic acid (CAS 3237-44-3)
Synonym :
2-Hydroxy-2-isopropylsuccinic acid
Application :
2-Isopropylmalic acid is an isopropyl substituted malic acid
CAS:
3237-44-3
Purity:
≥98%
Molecular Weight:
176.17
Formula :
C7H12O5
Physical state:
Solid
solubility :
Shipping Condition :
Store at room temperature
Melting point:
144-146° C (lit.)
SMILES:
CC(C)C(CC(=O)O)(C(=O)O)O
References:
:2-Isopropylmalate and 3-isopropylmalate as intermediates in leucine biosynthesis. | CALVO, JM., et al. 1962. Biochemistry. 1: 1157-61. PMID: 14017963Secretion of an aluminum chelator, 2-isopropylmalic acid, by the budding yeast, Saccharomyces cerevisiae. | Kobayashi, A., et al. 2005. J Inorg Biochem. 99: 1260-3. PMID: 15833351Reduction of aluminum toxicity by 2-isopropylmalic acid in the budding yeast Saccharomyces cerevisiae. | Suzuki, T., et al. 2007. Biol Trace Elem Res. 120: 257-63. PMID: 17916978Extensive metabolic cross-talk in melon fruit revealed by spatial and developmental combinatorial metabolomics. | Moing, A., et al. 2011. New Phytol. 190: 683-96. PMID: 21275993Oxidative stress is a consequence, not a cause, of aluminum toxicity in the forage legume Lotus corniculatus. | Navascués, J., et al. 2012. New Phytol. 193: 625-636. PMID: 22136521Highly sensitive and selective detection of Al(III) ions in aqueous buffered solution with fluorescent peptide-based sensor. | In, B., et al. 2016. Bioorg Med Chem Lett. 26: 4477-4482. PMID: 27503680Identifying biomarkers for asthma diagnosis using targeted metabolomics approaches. | Checkley, W., et al. 2016. Respir Med. 121: 59-66. PMID: 27888993Chiral separation of disease biomarkers with 2-hydroxycarboxylic acid structure. | Calderón, C., et al. 2018. J Sep Sci. 41: 1224-1231.Buy1373253-24-7 PMID: 29205897Identification and quantification of new isomers of isopropyl-malic acid in wine by LC-IT and LC-Q-Orbitrap.Price of 2,3-Dihydropyran-6-one | Ricciutelli, M.PMID:33580805 , et al. 2019. Food Chem. 294: 390-396. PMID: 31126479Quantification of 2- and 3-isopropylmalic acids in forty Italian wines by UHPLC-MS/MS triple quadrupole and evaluation of their antimicrobial, antioxidant activities and biocompatibility. | Ricciutelli, M., et al. 2020. Food Chem. 321: 126726. PMID: 32259735Determination of coeluted isomers in wine samples by application of MS/MS deconvolution analysis. | Menicatti, M., et al. 2020. J Mass Spectrom. 55: e4607. PMID: 326777492-IPMA Ameliorates PM2.5-Induced Inflammation by Promoting Primary Ciliogenesis in RPE Cells. | Choi, JY., et al. 2021. Molecules. 26: PMID: 34500843Primary Ciliogenesis by 2-Isopropylmalic Acid Prevents PM2.5-Induced Inflammatory Response and MMP-1 Activation in Human Dermal Fibroblasts and a 3-D-Skin Model. | Bae, JE., et al. 2021. Int J Mol Sci. 22: PMID: 34681602Taxonomic and Metagenomic Analyses Define the Development of the Microbiota in the Chick. | Bogomolnaya, L., et al. 2023. mBio. 14: e0244422. PMID: 36475774