Product Name :
3-Hydroxy-3-methylglutaric Anhydride (CAS 34695-32-4)
Synonym :
3-Hydroxy-3-methylpentane-1,5-dioic Anhydride; Dihydro-4-hydroxy-4-methyl-2H-pyran-2,6(3H)-dione; Dicrotalic Anhydride
Application :
3-Hydroxy-3-methylglutaric Anhydride is a useful hypocholersterolemic HMG CoA reductase
CAS:
34695-32-4
Purity:
Molecular Weight:
144.13
Formula :
C6H8O4
Physical state:
Solid
solubility :
Soluble in dichloromethane, ethyl acetate, methanol, and acetone.
Shipping Condition :
Store at -20° C
Melting point:
93-97° C
SMILES:
CC1(CC(=O)OC(=O)C1)O
References:
:Substrate and inhibitor specificity of 3-hydroxy-3-methylglutaryl-CoA reductase determined with substrate-analogue CoA-thioesters and CoA-thioethers. | Hupperich, M., et al. 1991. Biol Chem Hoppe Seyler. 372: 857-63. PMID: 1772599A Class of Reactive Acyl-CoA Species Reveals the Non-enzymatic Origins of Protein Acylation.166881-42-1 MDL No. | Wagner, GR.40161-54-4 SMILES , et al.PMID:33605416 2017. Cell Metab. 25: 823-837.e8. PMID: 28380375Crystal structures of the mitochondrial deacylase Sirtuin 4 reveal isoform-specific acyl recognition and regulation features. | Pannek, M., et al. 2017. Nat Commun. 8: 1513. PMID: 29138502Isolation and purification of 3-hydroxy-3-methylglutaryl-coenzyme A by ion-exchange chromatography. | Williamson, IP. and Rodwell, VW. 1981. J Lipid Res. 22: 184-7. PMID: 6163836