Product Name :
SMCR7L Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
dJ1104E15.3 HSU79252 Hypothetical protein LOC54471 MID51 MIEF1 mitochondrial dynamic protein MID51 mitochondrial dynamic protein of 51 kDa mitochondrial dynamics protein MID51 mitochondrial dynamics protein of 51 kDa mitochondrial elongation factor 1 展开
Function :
Mitochondrial outer membrane protein which regulates mitochondrial fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface independently of the mitochondrial fission FIS1 and MFF proteins. Regulates DNM1L GTPase activity and DNM1L oligomerization. Binds ADP and can also bind GDP, although with lower affinity. Does not bind CDP, UDP, ATP, AMP or GTP. Inhibits DNM1L GTPase activity in the absence of bound ADP. Requires ADP to stimulate DNM1L GTPase activity and the assembly of DNM1L into long, oligomeric tubules with a spiral pattern, as opposed to the ring-like DNM1L oligomers observed in the absence of bound ADP.1212086-74-2 Order Does not require ADP for its function in recruiting DNM1L.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
KLH conjugated synthetic peptide derived from human SMCR7L 201-300/463
Species reactivity:
Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, Zebrafish, Sheep
Verify application:
WB
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at -20℃ for one year.1340313-49-6 Purity Avoid repeated freeze/thaw cycles.PMID:33706652 The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
Storage buffer solution:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
51 KDa
Positive control :
Expression is relatively high in heart, skeletal muscle, pancreas and kidney.